There are many different views on what this seventy sevens could mean, but we might put them all under six major heads. The first view is the traditional messianic interpretation. This view holds that the final week is a reference to the ministry of Christ and the destruction of the Jerusalem temple. Jesus ultimately fulfills these seventy weeks.
Another popular view is the dispensationalist view. In this view there is a parenthesis between the 69th and 70th week. The first 69 weeks refer to the first coming of Christ and the 70th week is seen as the future seven-year tribulation period which culminates in the second coming of Christ. Almost the polar opposite of this view is the preterist view, which believes all of these events have already been fulfilled and relate to Jewish history, and likely terminated in 70 AD when the temple was destroyed.
The historical-critical interpretation views this as symbolic and figurative rather than a literal timeline. Many hold that the seventy weeks is symbolic of a complete period of judgment and restoration. Most in this camp will view the persecution of the Jews under Antiochus IV Epiphanes and the Maccabean revolt to be the fulfillment of Daniel’s words here. Many of the proponents of this view are modern critical scholars.
Another view is that these words here by Daniel are typological and foreshadowing prophecy that has multiple fulfillments. It might have a fulfillment in Antiochus IV, another fulfillment in the ministry of Christ and the destruction of Jerusalem, as well as a future fulfillment in the end times. This is an attractive view in that it blends the best of historical and futurist perspectives.
Finally, one might take a covenantal interpretation of this passage. It is somewhat similar to the Messianic view but here it is focused upon covenants. In this view the seventy weeks are seen as a complete period marking the culmination of God’s redemptive plan for Israel. The end of these weeks signals the establishment of the new covenant through the work of Christ.